This brief describes a successful model implemented in Eswatini wherein HIV-positive and treatment adherent mothers were recruited, trained, and compensated to liaise between communities and health facilities with the ultimate goal of ensuring all women enrolled in prevention of mother-to-child treatment were adherent to HIV medications and maternal and child health care from pregnancy through breastfeeding cessation.
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Protecting Lives, Sustaining Progress
Published March 2026
The following landscape analysis of maternal and child health, HIV prevention, diagnosis, and treatment, and the historic strength of U.S. leadership in global aid provides an overview of these key areas of global health and recommendations for U.S. Congressional engagement and prioritization.
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Topics:
Advocacy,
Children,
Global Health Security,
Health System Strengthening,
HIV,
Maternal and Child Health,
Mothers and Infants,
Women
Journal Articles
Birth Defects and Adverse Pregnancy Outcomes in Hospital-based Birth Surveillance in Eswatini
Published February 2025
Background The Botswana Tsepamo study identified an initial neural tube defect (NTD) safety signal with dolutegravir antiretroviral therapy (ART) exposure at conception. We conducted similar surveillance in 5 hospitals in Eswatini from September 2021 to September 2023 to evaluate the prevalence of birth defects and adverse pregnancy outcomes by maternal HIV status and ART regimen/timing. […]
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Countries:
Eswatini
Journal Articles
An integrated, multidisciplinary management team intervention to improve patient‑centeredness, HIV, and maternal‑child outcomes in Lesotho
Published December 2024
Background Reducing perinatal HIV transmission and optimizing maternal and child health (MCH) outcomes in high HIV prevalence settings is an urgent, but complex, priority. Extant interventions over-emphasize individual-level provider and patient behaviors, and neglect critical health systems-level changes. The ‘Integrated Management Team to Improve Maternal-Child Outcomes (IMPROVE)’ study implemented a three-part, patient-centered, health-systems- level intervention […]
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Topics:
Maternal and Child Health
Countries:
Lesotho