Completed | December 2017

A Multidisciplinary “Integrated Management Team to Improve Maternal-Child Outcomes (IMPROVE)” Intervention

to Improve Maternal and Child Outcomes and HIV Service and Antiretroviral Therapy Uptake and Retention in Lesotho

Overview

Country:

Lesotho

Subject Matter:

Community Approaches to Enhance HIV and MNCH Services; Maternal, Newborn, and Child Health; Pediatric and Adolescent Testing, Care, and Treatment; PMTCT and HIV-free Survival

This study, supported by USAID’s Project SOAR, aimed to improve maternal and child health (MCH) outcomes by implementing and evaluating a multidisciplinary “Integrated Management Team to Improve Maternal-Child Outcomes (IMPROVE)” intervention to increase MCH, antiretroviral therapy (ART), and HIV services uptake and retention in Lesotho. Mixed methods were used to evaluate maternal and infant outcomes, as well as the feasibility and acceptability of integrating this intervention into routine national health systems.

Data Collection Period: July 2016 – July 2019

  1. Findings presented at the 10th International AIDS Society Conference, July 2019: “Adverse pregnancy outcomes among HIV-positive women in the era of universal antiretroviral therapy (ART) remain elevated compared with HIV-negative women in Lesotho“
  2. Findings presented at the 27th Conference on Retroviruses and Opportunistic Infections, March 2020: “High Viral Suppression among HIV-positive Postpartum Women: Cluster Randomized Trial“
  3. Findings presented at the 12th International Workshop on HIV & Pediatrics, November 2020: “Depression and Internalized Stigma in Pregnant and Recently Postpartum Women in Lesotho“
  4. Findings presented at the 12th International Workshop on HIV & Pediatrics, November 2020: “Results of a Cluster Randomized Study to Evaluate the Effect of a Comprehensive Service Delivery Intervention on HIV and Maternal and Child Health Outcomes in HIV-Positive and HIV-Negative Women“
  5. Findings presented at the 11th International AIDS Society Conference, July 2021: “Determinants of HIV-free survival in the era of lifelong universal antiretroviral therapy (ART): pooled analysis of PEAWIL and IMPROVE studies, Lesotho“
  6. Findings presented at the 13th International Workshop on HIV Pediatrics, July 2021: “Determinants of HIV-free survival in the era of lifelong universal antiretroviral therapy (ART): pooled analysis of PEAWIL and IMPROVE studies, Lesotho”
  7. Findings published in The Pediatric Infectious Disease Journal, September 2021: “Adverse Pregnancy Outcomes Among HIV-positive Women in the Era of Universal Antiretroviral Therapy Remain Elevated Compared With HIV-negative Women“

Explore Other Research

In Analysis Birth Surveillance in Eswatini Following Transition To Dolutegravir-based Treatment Maternal, Newborn, and Child Health; PMTCT and HIV-free Survival
Ongoing Data Collection Pediatric HIV community case finding and assessment of PMTCT effectiveness in Lesotho PMTCT and HIV-free Survival
In Analysis Assessing the Effectiveness of Integration of Rapid Antigen Testing for SARS-CoV-2 in MNCH, HIV and TB Services in Cameroon and Kenya: A Pre- and Post- Implementation Evaluation (Effectiveness Integration) Adult Testing, Care, and Treatment; COVID-19; Pediatric and Adolescent Testing, Care, and Treatment
All Research