New Horizons Advancing Pediatric HIV Care Collaborative

Introduction Even in the context of widespread access to prevention of vertical HIV transmission (PVT) services, health system challenges compromise health outcomes for women living with HIV and their children. The “Integrated Management Team to Improve Maternal-Child Outcomes” (IMPROVE) study measured the effect of a package of facility-based interventions on PVT and maternal and child […]

Introduction Incorporating SARS-CoV-2 antigen-detecting rapid diagnostic tests (Ag-RDTs) into routine care settings can facilitate efficient case identification and management in low-resource settings. We assessed the time required to complete SARS-CoV-2 screening and Ag-RDT testing in maternal, neonatal and child health (MNCH), HIV and tuberculosis clinics in selected facilities in Kenya and Cameroon. Methods We conducted […]

Background The Botswana Tsepamo study identified an initial neural tube defect (NTD) safety signal with dolutegravir antiretroviral therapy (ART) exposure at conception. We conducted similar surveillance in 5 hospitals in Eswatini from September 2021 to September 2023 to evaluate the prevalence of birth defects and adverse pregnancy outcomes by maternal HIV status and ART regimen/timing. […]