Ideas & Impact › Resources › Advanced HIV Disease Brief

Though incredible gains have been made to control HIV and AIDS epidemics, AIDS-related deaths have plateaued. Those facing the greatest risk of mortality and morbidity are the individuals living with advanced HIV disease. The burden of advanced HIV disease is significant and the health risks faced by those living with HIV are great. The Elizabeth Glaser Pediatric AIDS Foundation (EGPAF) has been working to build innovative models to respond to the health needs of all individuals at risk of, or infected with HIV, including those diagnosed with advanced HIV disease. This fact sheet highlights why advanced HIV disease requires urgent attention, and health programming and services that can prevent and treat advanced disease.

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Journal Articles

Tuberculosis Preventive Treatment Uptake Among Patients Initiating Antiretroviral Therapy in Malawi: Children Left Behind

Published November 2025

Background: Tuberculosis preventive treatment (TPT) is recommended for people living with HIV (PLHIV) to reduce the tuberculosis (TB) incidence in regions with a high prevalence of TB. We evaluated the uptake and completion of TPT among newly initiated antiretroviral therapy (ART) patients in a programme setting in Malawi. Objectives: To describe TPT initiation and completion rates, and […]

Topics:

Pediatric Tuberculosis (TB),

Tuberculosis (TB)

Countries:

Malawi

Project Brief

Integrating Nurturing Care for Early Childhood Development into Primary Health Care: The Tanzania Experience

Published July 2025

Overview More than 275 million children in low- and middle-income countries are at risk of suboptimal development, including over 66% of children in sub-Saharan Africa. In Tanzania 43% of children are at high risk of not achieving their full potential for growth and development. Risk factors for suboptimal development include poverty, nutritional deficiencies, maternal depression, […]

Countries:

Tanzania

Journal Articles

Accelerating Access to Paediatric Medicines

Published April 2025

Overview Despite progress in reducing neonatal and child mortality, access to age-appropriate medicines remains inequitable, particularly in low-income and middle-income countries. The Global Accelerator for Paediatric Formulations (GAP-f), a WHO-hosted network established in 2020, addresses these gaps by uniting 33 partners to promote innovation and access to child-friendly formulations. Phase 2 (2022–24) of GAP-f’s work […]