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Journal Articles
Tuberculosis Preventive Treatment Uptake Among Patients Initiating Antiretroviral Therapy in Malawi: Children Left Behind
Published November 24, 2025
Background: Tuberculosis preventive treatment (TPT) is recommended for people living with HIV (PLHIV) to reduce the tuberculosis (TB) incidence in regions with a high prevalence of TB. We evaluated the uptake and completion of TPT among newly initiated antiretroviral therapy (ART) patients in a programme setting in Malawi. Objectives: To describe TPT…
Topics:
Pediatric Tuberculosis (TB),
Tuberculosis (TB)
Countries:
Malawi
Project Brief
Integrating Nurturing Care for Early Childhood Development into Primary Health Care: The Tanzania Experience
Published July 23, 2025
Overview More than 275 million children in low- and middle-income countries are at risk of suboptimal development, including over 66% of children in sub-Saharan Africa. In Tanzania 43% of children are at high risk of not achieving their full potential for growth and development. Risk factors for suboptimal development include…
Countries:
Tanzania
Journal Articles
Accelerating Access to Paediatric Medicines
Published April 15, 2025
Overview Despite progress in reducing neonatal and child mortality, access to age-appropriate medicines remains inequitable, particularly in low-income and middle-income countries. The Global Accelerator for Paediatric Formulations (GAP-f), a WHO-hosted network established in 2020, addresses these gaps by uniting 33 partners to promote innovation and access to child-friendly formulations. Phase…
Resource
Effectiveness of a Multi-component Facility-based Intervention on HIV-related Infant and Maternal Outcomes
Published April 6, 2025
Introduction Even in the context of widespread access to prevention of vertical HIV transmission (PVT) services, health system challenges compromise health outcomes for women living with HIV and their children. The “Integrated Management Team to Improve Maternal-Child Outcomes” (IMPROVE) study measured the effect of a package of facility-based interventions on…
Countries:
Lesotho
Journal Articles
Assessing Time Requirements of Two Models of SARS-CoV- 2 Screening and Testing in Routine Healthcare Services in Kenya and Cameroon
Published March 23, 2025
Introduction Incorporating SARS-CoV-2 antigen-detecting rapid diagnostic tests (Ag-RDTs) into routine care settings can facilitate efficient case identification and management in low-resource settings. We assessed the time required to complete SARS-CoV-2 screening and Ag-RDT testing in maternal, neonatal and child health (MNCH), HIV and tuberculosis clinics in selected facilities in Kenya…
Countries:
Cameroon,
Kenya
Resource
Using an App for COVID-19 Contact Tracing Costs Less Per Person Traced Than Manual Tracing
Published February 19, 2025
Introduction SARS-CoV-2 contact tracing in Cameroon has been done manually using paper forms and phone calls. However, there were reports of inaccurate contact details, resulting in delays in identifying and testing contacts. A recently introduced digital contact-tracing module using the Mamal Pro app automatically sends SMS messages to notify all…
Countries:
Cameroon
Journal Articles
Birth Defects and Adverse Pregnancy Outcomes in Hospital-based Birth Surveillance in Eswatini
Published February 2, 2025
Background The Botswana Tsepamo study identified an initial neural tube defect (NTD) safety signal with dolutegravir antiretroviral therapy (ART) exposure at conception. We conducted similar surveillance in 5 hospitals in Eswatini from September 2021 to September 2023 to evaluate the prevalence of birth defects and adverse pregnancy outcomes by maternal…
Countries:
Eswatini
Resource
Barriers and facilitators to implementing six monthly multi-month dispensing of antiretroviral therapy in two urban HIV clinics during the COVID-19 Era in Malawi
Published January 20, 2025
Overview Following the COVID-19 pandemic, the Malawi Government released a policy that promoted the scale-up of six-monthly multi-month dispensing (6-MMD) of antiretroviral therapy (ART) to people living with HIV in order to decrease congestion at health facilities and transmission of COVID-19. We evaluated the barriers and facilitators to implementing the…
Countries:
Malawi
Journal Articles
A Cross-Sectional Study of the Use of Antigen Rapid Diagnostic Tests for Community Identification of Severe Acute Respiratory Syndrome Coronavirus-2 in Kenya
Published January 20, 2025
Overview Mass testing with antigen-detecting rapid diagnostic tests (Ag-RDT), including testing of asymptomatic individuals, is expected to improve the identification of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) infections. Mass testing was offered at large gatherings to determine the SARS-CoV-2 case detection rate and the acceptance and cost of implementing this…
Countries:
Kenya