This issue of our annual newsletter describes EGPAF’s early beginnings as a research organization devoted to the discovery of treatment options for HIV-positive children and highlights our continuing operations research of HIV/AIDS programs in supported countries.
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Journal Articles
Breastfeeding, Antiretroviral Therapy, HIV Transmission, and the HIV Reservoir
Published October 2024
Recommendations on breastfeeding by persons living with HIV (PLWH) have shifted globally over time. Because the absolute risk for HIV transmission through breast milk in the absence of antiretroviral therapy (ART) is as high as 16% to 20%, recommendations for low-resource settings in the early 1990s initially emphasized replacement feeding if acceptable, feasible, affordable, sustainable, […]
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Topics:
Prevention of Mother-to-Child Transmission (PMTCT),
Research
Journal Articles
The Rollout of Paediatric Dolutegravir and Virological Outcomes Among Children Living with HIV in Mozambique
Published July 2024
Background In 2022, Mozambique introduced Dolutegravir 10mg (pDTG), as part of paediatric antiretroviral therapy for children weighing < 20 kg. Understanding real-world challenges during national rollout can strengthen health systems in resource-limited settings. Objectives We described the transition rate to, and new initiation of, pDTG, viral load suppression (VLS) post-pDTG, and factors associated with VLS […]
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Topics:
Pediatric HIV,
Research
Countries:
Mozambique
Journal Articles
Lessons from a Decade of Adult Vaccine Rollout in Low- and Middle-income Countries
Published June 2024
Introduction The historical focus of vaccines on child health coupled with the advent of novel vaccines targeting adult populations necessitates exploring strategies for adult vaccine implementation. Areas covered This scoping review extracts insights from the past decade’s experiences introducing adult vaccines in low- and middle-income countries. Among 25 papers reviewed, 19 focused on oral cholera […]
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Topics:
Research