Search Results
(
)
Filter by
Filter by health areas, people and populations, or solutions
Filter by EGPAF’s stories, research, resources or news
Journal Articles
Breastfeeding, Antiretroviral Therapy, HIV Transmission, and the HIV Reservoir
Published October 8, 2024
Recommendations on breastfeeding by persons living with HIV (PLWH) have shifted globally over time. Because the absolute risk for HIV transmission through breast milk in the absence of antiretroviral therapy (ART) is as high as 16% to 20%, recommendations for low-resource settings in the early 1990s initially emphasized replacement feeding…
Topics:
Prevention of Mother-to-Child Transmission (PMTCT),
Research
Journal Articles
The Rollout of Paediatric Dolutegravir and Virological Outcomes Among Children Living with HIV in Mozambique
Published July 30, 2024
Background In 2022, Mozambique introduced Dolutegravir 10mg (pDTG), as part of paediatric antiretroviral therapy for children weighing < 20 kg. Understanding real-world challenges during national rollout can strengthen health systems in resource-limited settings. Objectives We described the transition rate to, and new initiation of, pDTG, viral load suppression (VLS)…
Topics:
Pediatric HIV,
Research
Countries:
Mozambique
Journal Articles
Lessons from a Decade of Adult Vaccine Rollout in Low- and Middle-income Countries
Published June 27, 2024
Introduction The historical focus of vaccines on child health coupled with the advent of novel vaccines targeting adult populations necessitates exploring strategies for adult vaccine implementation. Areas covered This scoping review extracts insights from the past decade’s experiences introducing adult vaccines in low- and middle-income countries. Among 25 papers reviewed,…
Topics:
Research
Journal Articles
Consistency of Multi-Month Antiretroviral Therapy Dispensing and Association with Viral Load Coverage Among Pediatric Clients Living with HIV in Mozambique
Published June 25, 2024
Abstract With the increase in uptake of multi-month antiretroviral therapy dispensing (MMD) for children, little is known about consistency of MMD receipt over time and its association with virological outcomes. This analysis aims to assess the uptake of 3-month MMD among children, consistent receipt of MMD after uptake, and clinical…
Topics:
Differentiated Service Delivery,
Pediatric HIV,
Research
Countries:
Mozambique
Journal Articles
Enhancing SARS-CoV- 2 surveillance in Malawi using telephone syndromic surveillance from July 2020 to April 2022
Published May 16, 2024
Introduction Monitoring the SARS-CoV-2 pandemic in low-resource countries such as Malawi requires cost-effective surveillance strategies. This study explored the potential utility of phone-based syndromic surveillance in terms of its reach, monitoring trends in reported SARS-CoV-2-like/influenza-like symptoms (CLS/ILS), SARS-CoV-2 testing and mortality. Methods Mobile phone-based interviews were conducted between 1 July…
Topics:
Global Health Security,
Research
Countries:
Malawi
Journal Articles
Unlocking the Potential
Published April 30, 2024
Background The introduction of dolutegravir (DTG) in treating HIV has shown enhanced efficacy and tolerability. This study examined changes in weight gain and body mass index (BMI) at 6- and 12-months after post-initiating antiretroviral therapy (ART), comparing people living with HIV (PLHIV) on DTG-based regimens with those on non- DTG-based…
Topics:
Research
Countries:
Malawi
Journal Articles
Early Effects of Scaling Up Dolutegravir‑Based ARV Regimens Among Children Living with HIV in Malawi
Published April 17, 2024
Viral suppression (VS) in children has remained suboptimal compared to that in adults. We evaluated the impact of transitioning children weighing < 20 kg to a pediatric formulation of dolutegravir (pDTG) on VS in Malawi. We analyzed routine retrospective program data from electronic medical record systems pooled across 169 healthcare…
Topics:
HIV,
Pediatric HIV,
Research
Countries:
Malawi