Ideas & Impact › Resources › Clinical effect and cost-effectiveness of incorporation of point-of-care assays into early infant HIV diagnosis programmes in Zimbabwe

Using the Cost Effectiveness of Preventing AIDS Complications (CEPAC)—Pediatric model, the study team examined the clinical benefits, costs, and cost-effectiveness of replacing conventional assays for early infant HIV diagnosis with point-of-care (POC) assays at age 6 weeks in Zimbabwe. Compared with conventional assays, POC assays for early infant HIV diagnosis in Zimbabwe were found to improve survival, extend life expectancy of HIV-exposed infants. They are also more cost-effective than conventional assays.

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Issue Briefs

Accelerating Progress to Ending Pediatric HIV

Published March 2026

We are at a critical inflection point for children affected by HIV. In 2024 alone, 120,000 children were newly infected, and, without timely treatment, half of HIV positive infants will not reach their second birthday. Children remain left behind—a child with HIV is 6 times more likely to die than an adult without timely diagnosis. […]

Topics:

HIV,

Pediatric HIV

Countries:

Global

Resource

Protecting Lives, Sustaining Progress

Published March 2026

The following landscape analysis of maternal and child health, HIV prevention, diagnosis, and treatment, and the historic strength of U.S. leadership in global aid provides an overview of these key areas of global health and recommendations for U.S. Congressional engagement and prioritization.

Topics:

Advocacy,

Children,

Global Health Security,

Health System Strengthening,

HIV,

Maternal and Child Health,

Mothers and Infants,

Women

Journal Articles

Follow-Up Outcomes of Children, Adolescents, and Young People on Darunavir-Based Third-Line Antiretroviral Therapy

Published October 2024

Background: We assessed clinical outcomes among children, adolescents, and people younger than 25 years on darunavir-based antiretroviral therapy (ART) in 9 sub-Saharan African countries. Setting: Third-line ART centers in Cameroon, Eswatini, Kenya, Lesotho, Nigeria, Rwanda, Uganda, Zambia, and Zimbabwe. Methods: From January 2019 to December 2022, we collected data from a cohort of children, adolescents, and young people […]

Topics:

Adolescents,

Pediatric HIV

Countries:

Cameroon,

Eswatini,

Kenya,

Lesotho,

Nigeria,

Rwanda,

Uganda,

Zambia,

Zimbabwe