We are at a critical inflection point for children affected by HIV.
In 2024 alone, 120,000 children were newly infected, and, without timely treatment, half of HIV positive infants will not reach their second birthday. Children remain left behind—a child with HIV is 6 times more likely to die than an adult without timely diagnosis. The science and the tools exist to eliminate pediatric HIV, syphilis, and hepatitis B from birth. The gap is in innovation adoption, implementation with fidelity, scale, and system capacity.
The Elizabeth Glaser Pediatric AIDS Foundation (EGPAF) is launching an ambitious 2026–2028 strategy to change this trajectory. Building on 36 years of partnership with governments—having reached 33 million pregnant women and prevented over 410,000 pediatric infections—we are doubling down on eliminating vertical transmission, ending pediatric AIDS, and achieving HIV-free survival through strengthening maternal and child health systems at scale.
With targeted government and donor partnership, EGPAF will support countries to reach the World Health Organization’s (WHO) elimination milestones—mother to child transmission rates (MTCT) under 5%, fewer than 50 infections per 100,000 births, and HBV prevalence under 0.1% in children under 5—while driving progress toward 95 95 95 outcomes for pregnant women, children, and adolescents.
Our strategy centers on four high-impact pathways, working with government and actively integrating digital health solutions:
Bridging solutions
Catalytic service delivery
Evidence generation and strategic data use
Advocacy and policy influence
Children Cannot Be Left Behind in the Fight Against HIV
Learn how EGPAF’s 2026–2028 strategy will scale innovation, strengthen health systems, and partner with governments to eliminate pediatric HIV and improve outcomes for mothers and children.
