A cross-sectional prevalence survey will be carried out during the 33rd AFCON in Cameroon in January and February 2022. The study will take place in the Littoral and Center regions (Douala and Yaoundé), in the fan zones dedicated to the AFCON supporters. Mandatory SARS-Cov-2 Ag-RDT will be offered to all supporters attending the selected fan zones. Those testing negative will be allowed to enter the fan zone and enjoy the match, while those testing positive will be denied access to the fan zone by the MoH sanitary pass controllers. A Reverse Transcriptase Polymerase Chain Reaction (PCR) test will be offered to supporters with a positive SARS-Cov-2 Ag-RDT result. Among those who consent, the sample for this PCR test will also serve as the sample used to perform whole genome sequencing for strain identification and characterization. The objectives of the study are as follows:
Primary objectives:
1. To determine the SARS-CoV-2 case detection rate (number of SARS-CoV2 infections detected per 10,000 individuals tested) among potential study Fan Zone attendees using SARS-CoV-2 Ag-RDT during the Africa Cup of Nations.
2. To describe trends on SARS-CoV-2 positivity rate among potential study Fan Zone attendees tested over approximately 2-4 weeks during the Africa Cup of Nations using SARS-CoV-2 Ag-RDT.
Secondary objectives:
3. To describe symptom and comorbidity profiles of attendees with SARS-CoV-2 infection and to describe factors associated with infection, such as demographics, exposure risk, and vaccination status.
4. To describe SARS-CoV-2 variants among SARS-CoV-2 positive attendee