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Journal Articles
Breastfeeding, Antiretroviral Therapy, HIV Transmission, and the HIV Reservoir
Published October 8, 2024
Recommendations on breastfeeding by persons living with HIV (PLWH) have shifted globally over time. Because the absolute risk for HIV transmission through breast milk in the absence of antiretroviral therapy (ART) is as high as 16% to 20%, recommendations for low-resource settings in the early 1990s initially emphasized replacement feeding…
Topics:
Prevention of Mother-to-Child Transmission (PMTCT),
Research
Issue Briefs
Action Towards a HIV-Free Future
Published September 30, 2024
The urgency of addressing the health needs of children has never been more pressing. Despite significant gains in preventing vertical transmission of HIV, progress has stalled. New HIV infections in children continue to be unacceptably high: In 2023, there were approximately 120,000 new HIV infections among children under five years…
Topics:
Prevention of Mother-to-Child Transmission (PMTCT)
Resource
Looking Forward
Published September 15, 2024
Topics:
Adolescents,
Pediatric HIV,
Prevention of Mother-to-Child Transmission (PMTCT)
Journal Articles
The Rollout of Paediatric Dolutegravir and Virological Outcomes Among Children Living with HIV in Mozambique
Published July 30, 2024
Background In 2022, Mozambique introduced Dolutegravir 10mg (pDTG), as part of paediatric antiretroviral therapy for children weighing < 20 kg. Understanding real-world challenges during national rollout can strengthen health systems in resource-limited settings. Objectives We described the transition rate to, and new initiation of, pDTG, viral load suppression (VLS)…
Topics:
Pediatric HIV,
Research
Countries:
Mozambique
Journal Articles
Lessons from a Decade of Adult Vaccine Rollout in Low- and Middle-income Countries
Published June 27, 2024
Introduction The historical focus of vaccines on child health coupled with the advent of novel vaccines targeting adult populations necessitates exploring strategies for adult vaccine implementation. Areas covered This scoping review extracts insights from the past decade’s experiences introducing adult vaccines in low- and middle-income countries. Among 25 papers reviewed,…
Topics:
Research
Journal Articles
Consistency of Multi-Month Antiretroviral Therapy Dispensing and Association with Viral Load Coverage Among Pediatric Clients Living with HIV in Mozambique
Published June 25, 2024
Abstract With the increase in uptake of multi-month antiretroviral therapy dispensing (MMD) for children, little is known about consistency of MMD receipt over time and its association with virological outcomes. This analysis aims to assess the uptake of 3-month MMD among children, consistent receipt of MMD after uptake, and clinical…
Topics:
Differentiated Service Delivery,
Pediatric HIV,
Research
Countries:
Mozambique
Journal Articles
Enhancing SARS-CoV- 2 surveillance in Malawi using telephone syndromic surveillance from July 2020 to April 2022
Published May 16, 2024
Introduction Monitoring the SARS-CoV-2 pandemic in low-resource countries such as Malawi requires cost-effective surveillance strategies. This study explored the potential utility of phone-based syndromic surveillance in terms of its reach, monitoring trends in reported SARS-CoV-2-like/influenza-like symptoms (CLS/ILS), SARS-CoV-2 testing and mortality. Methods Mobile phone-based interviews were conducted between 1 July…
Topics:
Global Health Security,
Research
Countries:
Malawi