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Journal Articles
Tuberculosis Preventive Treatment Uptake Among Patients Initiating Antiretroviral Therapy in Malawi: Children Left Behind
Published November 24, 2025
Background: Tuberculosis preventive treatment (TPT) is recommended for people living with HIV (PLHIV) to reduce the tuberculosis (TB) incidence in regions with a high prevalence of TB. We evaluated the uptake and completion of TPT among newly initiated antiretroviral therapy (ART) patients in a programme setting in Malawi. Objectives: To describe TPT…
Topics:
Pediatric Tuberculosis (TB),
Tuberculosis (TB)
Countries:
Malawi
Journal Articles
HIV Drug Resistance Profile in Clients Experiencing Treatment Failure After the Transition to a Dolutegravir-Based First-Line Antiretroviral Treatment Regimen in Mozambique
Published January 8, 2025
Real-world data on HIV drug resistance (HIVDR) after transitioning to tenofovir disoproxil fumarate/lamivudine/dolutegravir (TLD) are limited. We assessed HIVDR rates and patterns in clients with virological failure (VF) after switching from an NNRTI-based regimen to TLD. A cross-sectional study was conducted in Gaza, Mozambique (August 2021–February 2022), including adults on…
Topics:
HIV
Countries:
Mozambique
Journal Articles
Examining teen club attendance and viral load suppression among adolescents under differentiated HIV care in Malawi
Published January 5, 2025
Background In Malawi, compared to adults, adolescents have higher rates of high HIV viremia and poorer antiretroviral therapy (ART) outcomes. The Ministry of Health, supported by the Elizabeth Glaser Pediatric AIDS Foundation (EGPAF), implemented the provision of differentiated care clubs for adolescents living with HIV (ALHIV), called “teen clubs,” to…
Topics:
Adolescents
Countries:
Malawi
Journal Articles
Improving HIV testing and retention among adolescents and youths
Published December 19, 2024
Adolescents and youth living with HIV (AYLHIV) often face significant challenges in HIV care. Elizabeth Glaser Pediatric AIDS Foundation in Malawi implemented the Red-Carpet Program (RCP) to provide fast-tracked services for AYLHIV in care.This study aimed to assess the effect of RCP on Provider-Initiated HIV testing, linkage to care and…
Topics:
Adolescents
Countries:
Malawi
Journal Articles
Effect of integrating paediatric tuberculosis services into child healthcare services on case detection in Africa
Published December 18, 2024
Introduction Paediatric tuberculosis (TB) underdiagnosis is a critical concern. The INPUT stepped-wedge cluster-randomised trial assessed the impact of integrating child TB services into child healthcare on TB case detection among children under age 5 years. Methods We compared the standard of care, providing TB care in specific TB clinics…
Topics:
Tuberculosis (TB)
Countries:
Cameroon,
Kenya
Program Tools
Breakthrough Champion Advocacy Toolkit
Published December 1, 2024
This Breakthrough Champion Advocacy Toolkit is targeted towards strengthening the capacity of adolescents and youth to advocate for addressing HIV treatment inequalities to end AIDS. The Toolkit serves as a training manual for the Breakthrough Partnership’s adolescent champions to develop advocacy skills and gain knowledge about HIV treatment gaps and…
Topics:
Adolescents
Countries:
Mozambique,
Nigeria,
Uganda
Journal Articles
Tuberculosis Infection in Children and Adolescents
Published October 31, 2024
The burden of tuberculosis (TB) in children and adolescents remains very significant. Several million children and adolescents are infected with TB each year worldwide following exposure to an infectious TB case and the risk of progression from TB infection to tuberculosis disease is higher in this group compared to adults.
Topics:
Tuberculosis (TB)
Journal Articles
Clients’ and providers’ perspectives in informing a digital health intervention to improve linkage to care after Index HIV self-testing in Hai and Moshi Districts, Tanzania
Published October 31, 2024
Background Digital health interventions have the potential to improve linkage to care after HIV self-testing (HIVST). This study aimed to understand clients’ and providers’ perceptions of benefits, and barriers of a digital health intervention designed to improve linkage to care after HIV self-testing in Tanzania. Methods This exploratory qualitative research…
Topics:
HIV
Countries:
Tanzania
Journal Articles
Decentralisation and integration of paediatric tuberculosis services to primary healthcare facilities as an approach to optimise management in Cameroon and Kenya
Published October 30, 2024
Introduction: Tuberculosis (TB) remains a major cause of morbidity and mortality for children less than 5 years. Diagnosis and treatment of children with active TB is often centralised in district hospital settings due to poor public health infrastructure and lack of diagnostic capabilities in primary healthcare (PHC) facilities. This analysis…
Topics:
Tuberculosis (TB)
Countries:
Cameroon,
Kenya