Tuberculosis is among the top-10 causes of mortality in children with more than 1 million children suffering from TB disease annually worldwide. The main challenge in young children is the difficulty in establishing an accurate diagnosis of active TB. The INPUT study is a stepped-wedge cluster-randomized intervention study aiming to assess the effectiveness of integrating TB services into child healthcare services on TB diagnosis capacities in children under 5 years of age. Study enrolments started in May 2019, enrolments will be completed in October 2020 and follow-up will be completed by June 2021. The study findings will be disseminated to national, regional and international audiences and will inform innovative approaches to integration of TB screening, diagnosis, and treatment initiation into child health care services.
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A cough monitor having a review meeting with a mother at ndhiwa Subcounty hospital.EGPAF worked in partnership with ministry of health Homabay county to implement CaP TB (Catalyzing Pediatric TB). CaP TB sought to reduce childhood illness and deaths due to TB in Homabay and Turkana counties by developing, implementing and documenting innovative models of care and catalyzing their wide-scale implementation to improve case detection and treatment.
Journal Articles
Innovations to improve identification of TB and SARS-CoV-2 infections in sub-Saharan Africa
Published July 2026
This supplement highlights research on integrated COVID-19 and tuberculosis services to improve diagnosis, care, and health system resilience in Cameroon and Kenya.
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Topics:
Research,
Tuberculosis (TB)
Countries:
Global
Child,Precious Ogweno accompanied by caregiver Leah Ogweno, at the TB clinic -HEI in Mbita sub county hospital, Mbita, Homabay. Photo by Kevin Ouma for EGPAF.
Journal Articles
Tuberculosis Preventive Treatment Uptake Among Patients Initiating Antiretroviral Therapy in Malawi: Children Left Behind
Published November 2025
Background: Tuberculosis preventive treatment (TPT) is recommended for people living with HIV (PLHIV) to reduce the tuberculosis (TB) incidence in regions with a high prevalence of TB. We evaluated the uptake and completion of TPT among newly initiated antiretroviral therapy (ART) patients in a programme setting in Malawi. Objectives: To describe TPT initiation and completion rates, and […]
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Topics:
Pediatric Tuberculosis (TB),
Tuberculosis (TB)
Countries:
Malawi
Journal Articles
Effect of integrating paediatric tuberculosis services into child healthcare services on case detection in Africa
Published December 2024
Introduction Paediatric tuberculosis (TB) underdiagnosis is a critical concern. The INPUT stepped-wedge cluster-randomised trial assessed the impact of integrating child TB services into child healthcare on TB case detection among children under age 5 years. Methods We compared the standard of care, providing TB care in specific TB clinics (control phase), with the Catalysing Paediatric […]
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Topics:
Tuberculosis (TB)
Countries:
Cameroon,
Kenya