Though incredible gains have been made to control HIV and AIDS epidemics, AIDS-related deaths have plateaued. Those facing the greatest risk of mortality and morbidity are the individuals living with advanced HIV disease. The burden of advanced HIV disease is significant and the health risks faced by those living with HIV are great. The Elizabeth Glaser Pediatric AIDS Foundation (EGPAF) has been working to build innovative models to respond to the health needs of all individuals at risk of, or infected with HIV, including those diagnosed with advanced HIV disease. This fact sheet highlights why advanced HIV disease requires urgent attention, and health programming and services that can prevent and treat advanced disease.
Explore Related Resources
A cough monitor having a review meeting with a mother at ndhiwa Subcounty hospital.EGPAF worked in partnership with ministry of health Homabay county to implement CaP TB (Catalyzing Pediatric TB). CaP TB sought to reduce childhood illness and deaths due to TB in Homabay and Turkana counties by developing, implementing and documenting innovative models of care and catalyzing their wide-scale implementation to improve case detection and treatment.
Journal Articles
Innovations to improve identification of TB and SARS-CoV-2 infections in sub-Saharan Africa
Published July 2026
This supplement highlights research on integrated COVID-19 and tuberculosis services to improve diagnosis, care, and health system resilience in Cameroon and Kenya.
View Resource
Topics:
Research,
Tuberculosis (TB)
Countries:
Global
Issue Briefs
Common Ground for Global Health Policy Brief: Pediatric HIV
Published June 2026
Overview Children* are disproportionately affected by the HIV epidemic yet are consistently deprioritized and underserved compared to other affected populations. UNAIDS’ global treatment targets call for 95% of people living with HIV to know their status; 95% of people who know their status to be on treatment; and 95% of people on treatment to sustain […]
View Resource
Topics:
Advocacy,
Pediatric HIV
Countries:
Global
Resource
Evidence for sustainable parenting and cash transfer programmes in Tanzania
Published June 2026
In Tanzania’s Dodoma region, EGPAF partnered on Kizazi Kijacho — meaning “Next Generation” in Swahili — a large-scale randomized controlled trial testing whether parenting support, cash transfers, or both could improve early childhood development outcomes across more than 3,100 families. The findings have direct implications for how governments design scalable, affordable ECD programs. Parenting support […]
View Resource
Topics:
Children,
Maternal and Child Health
Countries:
Tanzania