For the first time in history, ending pediatric HIV is not just possible — it’s within reach.
The Elizabeth Glaser Pediatric AIDS Foundation (EGPAF) has spent 37 years preventing pediatric HIV and has averted 410,000 new HIV cases.
But 330 children under 15 still acquire HIV daily.
Their mothers aren’t different from mothers anywhere. They want healthy babies. Many know their HIV status. Many have access to treatment. But final barriers can be nearly impossible to overcome in real-world conditions: difficulty adhering to medication when clinics are far, when stigma is real, when side effects are hard.
Generation Zero is our commitment to seize this moment and drive new pediatric HIV infections down to zero. We have the tools. We have the expertise. We have the partnerships.
What we need now is urgency.
Achieving Generation Zero means


moms worry about passing HIV to their babies


children worry about taking daily HIV medicine


new pediatric HIV cases occur
Our Solution
We’re embedded in 12 of the 18 highest-burden countries with systems built, providers trained, and supply chains ready. The innovations that solve those real-world barriers exist. The infrastructure exists. For the first time, they’re converging.
Watch this video from Dr. Doris Macharia to learn more.
Join the Movement
If you care about children, global health, or just solving solvable problems, you should care about achieving Generation Zero.
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This is how we get to Zero.
For the first time, we have everything needed to stop pediatric HIV before it starts. Proven tools. Trained health workers. Systems ready to reach families. Your donation supports EGPAF’s work to deliver lifesaving prevention, strengthen care, and protect the next generation. Give today and help ensure no child is born with HIV.