Prevention of Mother-to-Child Transmission

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Tenofovir Pre-Exposure Prophylaxis for Pregnant and Breastfeeding Women at Risk of HIV Infection: The Time is Now

Journal Articles

By Lynne M. Mofenson

In this Perspective, Lynne Mofenson discusses the implications of Mugwanya and colleagues' findings for protection of women against HIV infection during breastfeeding.

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Timing of initiation of antiretroviral therapy and adverse pregnancy outcomes: a systematic review and meta-analysis

Journal Articles

By Uthman, Nachega, Anderson, Kanters, Mills, Renaud, Essajee, Doherty, Mofenson

Although lifelong combination antiretroviral therapy (ART) is recommended for all individuals with HIV, few data exist for pregnancy outcomes associated with ART initiation before conception. This study assesses adverse pregnancy outcomes associated with ART initiated before conception compared with that of ART started after conception.

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Retention of mothers and infants in the prevention of mother-to-child transmission of HIV programme is associated with individual and facility-level factors in Rwanda

Journal Articles

By Woelk, Ndatimana, Behan, Mukaminega, Nyirabahizi, Hoffman, Mugwaneza, Ribakare, Amzel, Phelps

This study aims to investigate levels of retention at specified time periods along the prevention of mother-to-child transmission (PMTCT) cascade among mother-infant pairs as well as individual- and facility-level factors associated with retention.

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Lessons learned from the PMTCT program in Swaziland: challenges with accepting lifelong ART for pregnant and lactating women – a qualitative study

Journal Articles

By Katirayi, Chouraya, Kudiabor, Mahdi, Kieffer, Moland, Tylleskar

This study provides insight into the challenges of lifelong ART initiation among pregnant women under Option A in Swaziland.

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Catalyzing Expanded Access to Early Testing, Care and Treatment for HIV-Exposed Infants

Fact Sheets

By late 2019, the four-year, U.S. $63 million UNITAID/Elizabeth Glaser Pediatric AIDS Foundation (EGPAF) project aims to significantly increase the number of HIV-positive infants receiving life-saving treatment in nine project countries, and also develop robust global and national markets for affordable, effective and equitable HIV infant testing.

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Benefits and Risks of Antiretroviral Therapy for Perinatal HIV Prevention

Journal Articles

Randomized-trial data on the risks and benefits of antiretroviral therapy (ART) as compared with zidovudine and single-dose nevirapine to prevent transmission of the human immunodeficiency virus (HIV) in HIV-infected pregnant women with high CD4 counts are lacking.

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TIMIZA90 Project Factsheet

Fact Sheets

Timiza90 is a five-year (Oct 2016 to Sept 2021) U.S. Centres for Disease Control and Prevention (CDC)-funded Project which aims to support the implementation and expansion of high quality, sustainable, and comprehensive HIV prevention, care, and treatment programs.

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Improving Access to HIV Care & Treatment Through Decentralization & Integration in Kenya

Issue Briefs

This brief focuses on EGPAF’s Pamoja Project in Homabay in the four sub-counties in which the project operated, during the period October 2010 to September 2016.

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PAMOJA: Supporting the Implementation and Expansion of High Quality HIV Prevention, Care, and Treatment Activities at Facility and Community Level in Kenya

Technical Reports

This report focuses on The U.S. Centers for Disease Control and Prevention (CDC)-funded Pamoja Project (2010–2016), which strengthened management, oversight, and implementation of high-quality integrated, comprehensive, and sustainable HIV services in Kenya. Through Pamoja, the Elizabeth Glaser Pediatric AIDS Foundation in Kenya (EGPAF-Kenya) integrated the delivery of HIV prevention, care, and treatment services into maternal, neonatal, and child health (MNCH) settings, tuberculosis (TB) units, and general health service delivery sites to improve client access to and retention in HIV care and treatment.

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BRIDGING RURAL SUB-SAHARAN AFRICAN COMMUNITIES AND THE GLOBAL RESPONSE TO THE HIV AND AIDS EPIDEMIC

Issue Briefs

Lessons from the Advancing Community Level Action for Improved Maternal and Child Health and PMTCT (Project ACCLAIM).

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