Prevention of Mother-to-Child Transmission

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Detectable Viral Load in Late Pregnancy among Women in the Rwanda Option B+ PMTCT Program: Enrollment Results from the Kabeho Study

Journal Articles

This study explored the extent of viral suppression from a prevention of mother-to-child transmission of HIV program in Rwanda  among women enrolled in the Kigali Antiretroviral and Breastfeeding Assessment for the Elimination of HIV (Kabeho) Study.

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ACCLAIM Toolkit: Scaling Up Community Involvement in Maternal and Child Health and Prevention of Mother-to-Child HIV Transmission

Program Tools

A compilation of various tools (guidelines, standard operating procedures, presentations, job aids and forms) to enhance community involvement in MNCH and PMTCT services among men, women and community leaders. This toolkit showcases how to bring to scale three distinct approaches: “community days”, peer group mentorship and community leadership engagement. All were met with success in Zimbabwe, Swaziland and Lesotho and had a dramatic effect on number of pregnant women who attended antenatal care earlier in pregnancy and number of women who attended all recommended antenatal visits.

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The Linking Initiatives for Elimination of Pediatric HIV (LIFE) Program

Technical Reports

This report highlights an important five-year which successfully strengthened prevention of mother-to-child HIV transmission and delivery of reproductive health among women in Tanzania.

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A case study on joint community-facility review of PMTCT dashboards in Malawi

Technical Briefs

This case study is intended for programme managers and others who are interested in strategies for involving communities in the review and use of health information to help women and children stay in care and improve prevention of mother-to-child transmission of HIV (PMTCT) programme performance and outcomes.

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Cluster-Randomized Controlled Study of SMS Text Messages for Prevention of Mother-to-Child Transmission of HIV in Rural Kenya

Journal Articles

By Kassaye, Ong’ech, Sirengo, Kose, Matu, McOdida, Simiyu, Syengo, Muthama, Machekano5

Antiretroviral medications are key for prevention of mother-to-child transmission (PMTCT) of HIV, and transmission mitigation is affected by service delivery, adherence, and retention.

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Tenofovir Disoproxil Fumarate Safety for Women and their Infants During Pregnancy and Breastfeeding: Systematic Review

Journal Articles

By Mofenson, Baggaley, Mameletzis

Pregnant/lactating women in some sub-Saharan Africa settings are at substantial risk of HIV acquisition and could benefit from preexposure prophylaxis (PrEP) with tenofovir disoproxil fumarate (TDF), but safety data in pregnancy/lactation are limited.

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Tenofovir Pre-Exposure Prophylaxis for Pregnant and Breastfeeding Women at Risk of HIV Infection: The Time is Now

Journal Articles

By Lynne M. Mofenson

In this Perspective, Lynne Mofenson discusses the implications of Mugwanya and colleagues' findings for protection of women against HIV infection during breastfeeding.

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Tenofovir Pre-Exposure Prophylaxis for Pregnant and Breastfeeding Women at Risk of HIV Infection: The Time is Now

Journal Articles

By Lynne M. Mofenson

In this Perspective, Lynne Mofenson discusses the implications of Mugwanya and colleagues' findings for protection of women against HIV infection during breastfeeding.

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Timing of initiation of antiretroviral therapy and adverse pregnancy outcomes: a systematic review and meta-analysis

Journal Articles

By Uthman, Nachega, Anderson, Kanters, Mills, Renaud, Essajee, Doherty, Mofenson

Although lifelong combination antiretroviral therapy (ART) is recommended for all individuals with HIV, few data exist for pregnancy outcomes associated with ART initiation before conception. This study assesses adverse pregnancy outcomes associated with ART initiated before conception compared with that of ART started after conception.

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