Journal Articles | April 2019

Risks and Benefits of Dolutegravir- and Efavirenz-Based Strategies for South African Women With HIV of Child-Bearing Potential

A Modeling Study
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Overview

This study evaluated clinical outcomes of ART policies among women of child-bearing potential in South Africa. Specifically, it evaluated outcomes associated with (1) efavirenz for all women of childbearing potential, (2) dolutegravir for all women of childbearing potential; (3) World Health Organization (WHO)-recommended efavirenz without contraception or dolutegravir with contraception (WHO approach).

Created by:

Caitlin M. Dugdale, MD; Andrea L. Ciaranello, MD, MPH; Linda-Gail Bekker, MD, PhD; Madeline E. Stern, BA; Landon Myer, MBChB, PhD; Robin Wood, MMed, DSc (Med); Paul E. Sax, MD; Elaine J. Abrams, MD; Kenneth A. Freedberg, MD, MSc; and Rochelle P. Walensky, MD, MPH

Topics:

Dolutegravir & Pregnancy; Prevention of Mother-to-Child Transmission; Strategic Information, Evaluation & Research