Incidence of switching to second-line antiretroviral therapy and associated factors in children with HIV: an international cohort collaboration

Background: We assessed clinical outcomes among children, adolescents, and people younger than 25 years on darunavir-based antiretroviral therapy (ART) in 9 sub-Saharan African countries. Setting: Third-line ART centers in Cameroon, Eswatini, Kenya, Lesotho, Nigeria, Rwanda, Uganda, Zambia, and Zimbabwe. Methods: From January 2019 to December 2022, we collected data from a cohort of children, adolescents, and young people […]

An Unspoken Crisis: Children Are Being Left Behind In 2022, one child died every six seconds. The causes of most of those deaths were preventable. This is unacceptable. Whereas countries have the tools and knowledge to end preventable deaths and suffering in children, children face inequalities in access to health care. Parliamentarians play a critical […]

Most causes of deaths in children could be prevented with effective treatment and interventions that are feasible for implementation, even in resource-constrained settings. However, appropriate medicines to save and improve the lives of infants and children often do not exist, are unavailable, or are not quality assured. This puts children’s lives at risk, hindering the […]