High HIV incidence in the postpartum period sustains vertical transmission in settings with generalized epidemics: a cohort study in Southern Mozambique

Real-world data on HIV drug resistance (HIVDR) after transitioning to tenofovir disoproxil fumarate/lamivudine/dolutegravir (TLD) are limited. We assessed HIVDR rates and patterns in clients with virological failure (VF) after switching from an NNRTI-based regimen to TLD. A cross-sectional study was conducted in Gaza, Mozambique (August 2021–February 2022), including adults on first-line ART for ≥12 months […]

This Breakthrough Champion Advocacy Toolkit is targeted towards strengthening the capacity of adolescents and youth to advocate for addressing HIV treatment inequalities to end AIDS. The Toolkit serves as a training manual for the Breakthrough Partnership’s adolescent champions to develop advocacy skills and gain knowledge about HIV treatment gaps and differentiated service delivery — which […]

Recommendations on breastfeeding by persons living with HIV (PLWH) have shifted globally over time. Because the absolute risk for HIV transmission through breast milk in the absence of antiretroviral therapy (ART) is as high as 16% to 20%, recommendations for low-resource settings in the early 1990s initially emphasized replacement feeding if acceptable, feasible, affordable, sustainable, […]