Ideas & Impact › Resources › Congenital Cytomegalovirus and HIV Perinatal Transmission

This study assessed the presence, magnitude, and risk factors associated with congenital cytomegalovirus (cCMV) among infants born to HIV-infected women, who were not receiving antiretroviral drugs during pregnancy. The authors found that in-utero HIV infection appears to be a major risk factor for cCMV in infants whose mothers have not received combination antiretroviral therapy in pregnancy.

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Journal Articles

Follow-Up Outcomes of Children, Adolescents, and Young People on Darunavir-Based Third-Line Antiretroviral Therapy

Published October 2024

Background: We assessed clinical outcomes among children, adolescents, and people younger than 25 years on darunavir-based antiretroviral therapy (ART) in 9 sub-Saharan African countries. Setting: Third-line ART centers in Cameroon, Eswatini, Kenya, Lesotho, Nigeria, Rwanda, Uganda, Zambia, and Zimbabwe. Methods: From January 2019 to December 2022, we collected data from a cohort of children, adolescents, and young people […]

Topics:

Adolescents,

Pediatric HIV

Countries:

Cameroon,

Eswatini,

Kenya,

Lesotho,

Nigeria,

Rwanda,

Uganda,

Zambia,

Zimbabwe

Journal Articles

Breastfeeding, Antiretroviral Therapy, HIV Transmission, and the HIV Reservoir

Published October 2024

Recommendations on breastfeeding by persons living with HIV (PLWH) have shifted globally over time. Because the absolute risk for HIV transmission through breast milk in the absence of antiretroviral therapy (ART) is as high as 16% to 20%, recommendations for low-resource settings in the early 1990s initially emphasized replacement feeding if acceptable, feasible, affordable, sustainable, […]

Topics:

Prevention of Mother-to-Child Transmission (PMTCT),

Research

Issue Briefs

Building a Future of Health

Published October 2024

An Unspoken Crisis: Children Are Being Left Behind In 2022, one child died every six seconds. The causes of most of those deaths were preventable. This is unacceptable. Whereas countries have the tools and knowledge to end preventable deaths and suffering in children, children face inequalities in access to health care. Parliamentarians play a critical […]

Topics:

Pediatric HIV,

Tuberculosis (TB)