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Issue Briefs
Addressing Child & Adolescent Tuberculosis Case Finding Gaps in Africa
Published August 19, 2024
Tuberculosis (TB) remains a significant and ongoing public health challenge in Africa, with the continent bearing a disproportionate burden. Seventeen of the 30 countries with the highest TB burden globally are African nations.1 In 2022, an estimated 322,000 children and young adolescents (under 15 years) in…
Topics:
Advocacy,
Tuberculosis (TB)
Issue Briefs
Investing in Tuberculosis Control in Africa
Published August 19, 2024
In 2022, 1.3 million children became ill with tuberculosis (TB) and 250,000 children died of the illness globally. Africa is disproportionately burdened by TB, with 17 of the 30 highest TB burden countries located on the continent. The region reported 2.5 million new TB cases and 424,000 deaths from…
Topics:
Advocacy,
Tuberculosis (TB)
Journal Articles
The Rollout of Paediatric Dolutegravir and Virological Outcomes Among Children Living with HIV in Mozambique
Published July 30, 2024
Background In 2022, Mozambique introduced Dolutegravir 10mg (pDTG), as part of paediatric antiretroviral therapy for children weighing < 20 kg. Understanding real-world challenges during national rollout can strengthen health systems in resource-limited settings. Objectives We described the transition rate to, and new initiation of, pDTG, viral load suppression (VLS)…
Topics:
Pediatric HIV,
Research
Countries:
Mozambique
Project Brief
Building Health Systems Capacity to Manage Pediatric HIV
Published July 17, 2024
As countries work towards the UNAIDS 95-95-95 goals for HIV epidemic control, the third 95 of viral suppression becomes pivotal, especially for children and adolescents living with HIV (CALHIV). An estimated 10-20% of CALHIV have an unsuppressed viral load (VL) on their current first- or second-line antiretroviral therapy (ART)…
Topics:
Pediatric HIV
Countries:
Cameroon,
Eswatini,
Kenya,
Lesotho,
Nigeria,
Republic of the Congo,
Rwanda,
Uganda,
Zambia,
Zimbabwe
Project Brief
Building Health Systems Capacity Reaching HIV Epidemic Viral Suppression Targets in All Children and Adolescents
Published July 17, 2024
Great progress has been made by many countries in reaching the UN 95-95-95 targets for HIV epidemic control, and several countries are approaching or have achieved them. However, children and adolescents living with HIV (CALHIV) consistently fall behind adults in reaching these targets, and the third 95 target of sustained…
Topics:
Pediatric HIV
Countries:
Cameroon,
Eswatini,
Kenya,
Lesotho,
Nigeria,
Republic of the Congo,
Rwanda,
Uganda,
Zambia,
Zimbabwe
Journal Articles
‘We did not even know it was Tuberculosis’
Published July 9, 2024
Introduction Paediatric tuberculosis (TB) is often undiagnosed and under-reported. The Catalysing Paediatric TB (CaP-TB) programme provided integrated and decentralised TB screening and diagnosis services through multiple paediatric care entry points. This qualitative evaluation explores acceptability of the CaP-TB programme and existing knowledge and perceptions of paediatric TB. Methods A descriptive…
Topics:
Tuberculosis (TB)
Countries:
Cameroon,
Kenya
Journal Articles
Consistency of Multi-Month Antiretroviral Therapy Dispensing and Association with Viral Load Coverage Among Pediatric Clients Living with HIV in Mozambique
Published June 25, 2024
Abstract With the increase in uptake of multi-month antiretroviral therapy dispensing (MMD) for children, little is known about consistency of MMD receipt over time and its association with virological outcomes. This analysis aims to assess the uptake of 3-month MMD among children, consistent receipt of MMD after uptake, and clinical…
Topics:
Differentiated Service Delivery,
Pediatric HIV,
Research
Countries:
Mozambique
Technical Briefs
Technical Brief on Paediatric HIV Case-Finding
Published May 6, 2024
Despite global progress in HIV treatment for children, the gap between adult and paediatric treatment coverage continues to widen. This gap is driven primarily by barriers to HIV diagnosis in children, but in the past decade those barriers have shifted. At the start of the epidemic, the lack of access…
Topics:
Pediatric HIV
Journal Articles
Integration of HIV Testing in a Community Intervention for Tuberculosis Screening Among Household Contacts of Patients with Tuberculosis in Cameroon and Uganda
Published April 25, 2024
Introduction People living with HIV are considered at higher risk of developing severe forms of tuberculosis (TB) disease. Providing HIV testing to TB-exposed people is therefore critical. We present the results of integrating HIV testing into a community-based intervention for household TB contact management in Cameroon and Uganda. Methods Trained…
Topics:
Tuberculosis (TB)
Countries:
Cameroon,
Uganda