In 2001, the Elizabeth Glaser Pediatric AIDS Foundation (EGPAF) began working in Zambia to enhance access to HIV care and treatment services for both adults and children. Our work has shifted in Zambia over these last few years to focus on technical assistance and health systems strengthening. EGPAF currently operates three projects to ensure the elimination of HIV, the protection of children, and the survival of all HIV-positive children and adolescents.