Pediatric HIV and AIDS Research and Product Development
Photo: Mia Collis |
More than two decades ago, Elizabeth Glaser began lobbying the halls of Congress to call for more research for drugs to treat HIV/AIDS in children. What started as a mother’s fight to save her child became the Foundation’s mission that today advocates for children around the world to access the best prevention and care that science and medicine have to offer.
Today, HIV/AIDS research and pediatric drug development remain key priorities for the Foundation. In order to eliminate pediatric AIDS, research in both medical science and public health practice must be conducted to increase the effectiveness of HIV care and treatment and prevention of mother-to-child transmission (PMTCT) programs on the ground.
Learn more:
Pediatric HIV Vaccine Research
Nearly 1,200 children contract HIV every day, the vast majority through mother-to-child transmission of HIV. While efforts to prevent mother-to-child transmission (PMTCT) of HIV have dramatically reduced the number of infants born HIV-positive worldwide, eliminating pediatric AIDS will require innovative prevention strategies and research. A pediatric HIV vaccine would protect infants born to HIV-positive mothers against HIV infection during breastfeeding, as well as set the stage for lifetime immunity for all infants, creating the first generation protected from and free of HIV. The Foundation advocates for continued strong investment in HIV/AIDS research, including the development of a pediatric HIV vaccine, as the best hope for eliminating pediatric AIDS worldwide.
Photo: Jon Hrusa
Top
HIV/AIDS Operations Research
Photo: Georgina Goodwin |
The fight against HIV/AIDS demands not just scientific advances, but also effective and efficient service delivery. This requires far greater investment in operations research, to advance current public health practices and to improve the lives of women, children, and families living with HIV/AIDS.
The Foundation advocates for increased HIV/AIDS operations research to study how best to translate scientific knowledge about the prevention and treatment of HIV/AIDS into better and more widespread medical care. Specifically, the Foundation supports operations research around HIV care and treatment programs and prevention of mother-to-child transmission (PMTCT) to help eliminate pediatric HIV. The Foundation also works to ensure that operations research is prioritized under the President’s Emergency Plan for AIDS Relief (PEPFAR).
Read more about our work with PEPFAR.
Top
Pediatric Therapeutics: Drugs and Medical Devices
Photo: Nigel Barker LLC |
Children need medical products that are properly designed, formulated, and manufactured specifically for their unique needs. However, the majority of pediatric medicines and medical devices used for children are not tested or approved for pediatric use.
Over the last decade, the Foundation has played a lead role in working with the U.S. Congress and Administration to enact and implement legislation to dramatically increase the number of drugs tested and labeled for children – the
Best Pharmaceuticals for Children Act (BPCA) and the
Pediatric Research Equity Act (PREA). Together these laws compose a “carrot and stick” approach where manufacturers are both required and incentivized to conduct pediatric drug studies.
Building on the success of pediatric drug testing legislation, the Foundation also worked with the U.S. Congress, the American Academy of Pediatrics, and other children’s health advocates to enact the Pediatric Medical Device Safety and Improvement Act, which improves pediatric medical device development in the U.S.
Top