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Journal Articles

An integrated, multidisciplinary management team intervention to improve patient‑centeredness, HIV, and maternal‑child outcomes in Lesotho

Published December 22, 2024

Background Reducing perinatal HIV transmission and optimizing maternal and child health (MCH) outcomes in high HIV prevalence settings is an urgent, but complex, priority. Extant interventions over-emphasize individual-level provider and patient behaviors, and neglect critical health systems-level changes. The ‘Integrated Management Team to Improve Maternal-Child Outcomes (IMPROVE)’ study implemented a…

Topics:

Maternal and Child Health

Countries:

Lesotho

Journal Articles

Integrating SARS-CoV-2 rapid antigen testing in maternal, neonatal and child health, HIV, and TB clinics in Kenya and Cameroon

Published October 30, 2024

Introduction: Early diagnosis of SARS-CoV-2 infection is key to preventing severe disease and poor outcomes in vulnerable populations, such as pregnant women and people living with HIV or diagnosed with tuberculosis (TB). We assessed outcomes achieved with the integration of SARS-CoV-2 antigen-detecting rapid diagnostic testing (Ag-RDT) into maternal, neonatal and…

Topics:

Global Health Security,

Maternal and Child Health

Countries:

Cameroon,

Kenya

Journal Articles

A Longitudinal Assessment of Interruptions in HIV Clinic Visits and Virologic Failure among Pregnant and Postpartum Women in the Kabeho Study

Published October 30, 2024

Background: Antiretroviral therapy (ART) for women with HIV is recommended for life, yet most studies measure retention in HIV care and treatment as a binary outcome rather than patterns of intermittent clinic attendance. Pregnancy and the post-partum period are critical times to study interruptions in care, as retention among these women…

Topics:

Maternal and Child Health

Countries:

Rwanda

Journal Articles

Breastfeeding, Antiretroviral Therapy, HIV Transmission, and the HIV Reservoir

Published October 8, 2024

Recommendations on breastfeeding by persons living with HIV (PLWH) have shifted globally over time. Because the absolute risk for HIV transmission through breast milk in the absence of antiretroviral therapy (ART) is as high as 16% to 20%, recommendations for low-resource settings in the early 1990s initially emphasized replacement feeding…

Topics:

Prevention of Mother-to-Child Transmission (PMTCT),

Research

Issue Briefs

Action Towards a HIV-Free Future

Published September 30, 2024

The urgency of addressing the health needs of children has never been more pressing. Despite significant gains in preventing vertical transmission of HIV, progress has stalled. New HIV infections in children continue to be unacceptably high: In 2023, there were approximately 120,000 new HIV infections among children under five years…

Topics:

Prevention of Mother-to-Child Transmission (PMTCT)

Resource

Looking Forward

Published September 15, 2024

Topics:

Adolescents,

Pediatric HIV,

Prevention of Mother-to-Child Transmission (PMTCT)

Chest Xray

Issue Briefs

Investing in Tuberculosis Control in Africa

Published August 19, 2024

In 2022, 1.3 million children became ill with tuberculosis (TB) and 250,000 children died of the illness globally. Africa is disproportionately burdened by TB, with 17 of the 30 highest TB burden countries located on the continent. The region reported 2.5 million new TB cases and 424,000 deaths from…

Topics:

Advocacy,

Tuberculosis (TB)

Issue Briefs

Addressing Child & Adolescent Tuberculosis Case Finding Gaps in Africa

Published August 19, 2024

Tuberculosis (TB) remains a significant and ongoing public health challenge in Africa, with the continent bearing a disproportionate burden. Seventeen of the 30 countries with the highest TB burden globally are African nations.1 In 2022, an estimated 322,000 children and young adolescents (under 15 years) in…

Topics:

Advocacy,

Tuberculosis (TB)

Journal Articles

Evaluation of a Peer-support, ‘Mentor Mother’ Program in Gaza, Mozambique

Published March 26, 2024

Background Retention in prevention of mother-to-child transmission of HIV programs is critical to reduce vertical transmission. To addresses challenges with retention, Mozambique launched a peer-support program in 2018, in which HIV-positive mothers provide adherence support as mentor mothers (MMs) for HIV-positive pregnant and lactating women and HIV-exposed and…

Topics:

Prevention of Mother-to-Child Transmission (PMTCT)

Countries:

Mozambique