We’re working to end pediatric HIV and AIDS in Lesotho, and support the delivery of high-quality and comprehensive health services to women, men, and children.

Health Areas of Impact

HIV, TB, & Comprehensive Health Services

EGPAF began collaborating with Lesotho’s Ministry of Health in 2004. Through leadership from the Government of Lesotho and support from the U.S. President’s Emergency Plan for AIDS Relief (PEPFAR) and other partners, Lesotho significantly scaled-up access to comprehensive HIV services across the country. In June 2016, the country adopted World Health Organization guidelines recommending Treatment for All, allowing anyone diagnosed with HIV an opportunity to be immediately initiated on treatment for life. EGPAF, as a key partner, helped the country to adopt these guidelines and widely implement them.

The most recent Lesotho Population-based HIV Impact Assessment showed that Lesotho reached the UNAIDS 90-90-90 targets by 2020, with 90% of the population aware of their HIV status, 97% of those aware of their HIV status on treatment, and 92% of those on treatment virally suppressed.

 

EGPAF has contributed to this success by using a national-, district-, and site-level approach to deliver HIV services and provide technical assistance to the Ministry of Health. EGPAF-Lesotho currently supports 178 sites in 8 districts to implement a comprehensive package of HIV and TB services, advocates at the national level to inform health policies, and conducts research to inform improved programming. Another key aspect of EGPAF-Lesotho’s portfolio is external technical assistance, including the provision of technical assistance to local implementing partners, which builds local capacity for sustainable quality TB/HIV services and self-reliance.

Our Impact

Over 163,000 Individuals Tested for HIV

5,000 Mothers Provided PMTCT Services

205,000 individuals and over 5,000 children provided with ARTVs

Early Infant testing and diagnostics provision to almost 5,000 infants

kananelo, youth leader in lesotho

“We all aspire for the gift of an AIDS-free generation.”

“For those who were born with HIV, it is time to heal wounds of the past and build bridges to the brighter future. I can now proudly say to my son that HIV ended with us—because, with prevention of mother-to-child HIV transmission, an HIV-free generation is now a reality.”

Read Kananelo’s story

The Latest from Lesotho

Story

Young Mothers Rewrite the Story of Lesotho 

Published November 2025

Reabetsoe waves and laughs as his mother, Motšelisi Tsubane, 23, leans in, singing his name and dangling a homemade ball. Reabetsoe is a healthy 4-month-old, learning how to focus his eyes and move his arms and legs. He has transformed this family.   “My son likes it when I sing lullabies for him—you see him smile and act happy,” […]

Topics:

Children,

Prevention of Mother-to-Child Transmission (PMTCT),

Women

Countries:

Lesotho

Motšelisi poses with her mother and son at their home.

Story

The Strength of a Mother

Published April 2025

Motšelisi Tsubane is a 23-year-old mother from Lithabaneng, Berea, in northern Lesotho. Her 4-month-old son, Reabetsoe, is healthy and energetic.  “My son likes it when I sing lullabies for him, you’d see him smile and happy,” says Motšelisi.  As a single mother, Motšelisi has her challenges. She is unemployed and lives with her mother, ‘Mamotšelisi […]

Topics:

General

Countries:

Lesotho

Resource

Effectiveness of a Multi-component Facility-based Intervention on HIV-related Infant and Maternal Outcomes

Published April 2025

Introduction Even in the context of widespread access to prevention of vertical HIV transmission (PVT) services, health system challenges compromise health outcomes for women living with HIV and their children. The “Integrated Management Team to Improve Maternal-Child Outcomes” (IMPROVE) study measured the effect of a package of facility-based interventions on PVT and maternal and child […]

Countries:

Lesotho