This brief describes a successful model implemented in Eswatini wherein HIV-positive and treatment adherent mothers were recruited, trained, and compensated to liaise between communities and health facilities with the ultimate goal of ensuring all women enrolled in prevention of mother-to-child treatment were adherent to HIV medications and maternal and child health care from pregnancy through breastfeeding cessation.
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Journal Articles
Birth Defects and Adverse Pregnancy Outcomes in Hospital-based Birth Surveillance in Eswatini
Published February 2025
Background The Botswana Tsepamo study identified an initial neural tube defect (NTD) safety signal with dolutegravir antiretroviral therapy (ART) exposure at conception. We conducted similar surveillance in 5 hospitals in Eswatini from September 2021 to September 2023 to evaluate the prevalence of birth defects and adverse pregnancy outcomes by maternal HIV status and ART regimen/timing. […]
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Countries:
Eswatini
Journal Articles
An integrated, multidisciplinary management team intervention to improve patient‑centeredness, HIV, and maternal‑child outcomes in Lesotho
Published December 2024
Background Reducing perinatal HIV transmission and optimizing maternal and child health (MCH) outcomes in high HIV prevalence settings is an urgent, but complex, priority. Extant interventions over-emphasize individual-level provider and patient behaviors, and neglect critical health systems-level changes. The ‘Integrated Management Team to Improve Maternal-Child Outcomes (IMPROVE)’ study implemented a three-part, patient-centered, health-systems- level intervention […]
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Topics:
Maternal and Child Health
Countries:
Lesotho
Adolescents join for a field day at Lobamba clinic in Eswatini
Journal Articles
Follow-Up Outcomes of Children, Adolescents, and Young People on Darunavir-Based Third-Line Antiretroviral Therapy
Published October 2024
Background: We assessed clinical outcomes among children, adolescents, and people younger than 25 years on darunavir-based antiretroviral therapy (ART) in 9 sub-Saharan African countries. Setting: Third-line ART centers in Cameroon, Eswatini, Kenya, Lesotho, Nigeria, Rwanda, Uganda, Zambia, and Zimbabwe. Methods: From January 2019 to December 2022, we collected data from a cohort of children, adolescents, and young people […]
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Topics:
Adolescents,
Pediatric HIV
Countries:
Cameroon,
Eswatini,
Kenya,
Lesotho,
Nigeria,
Rwanda,
Uganda,
Zambia,
Zimbabwe